Govindasamy Mugesh (born 1970) is an Indian inorganic and physical chemist, a professor and the head of the Mugesh Laboratory attached to the department of Inorganic and Physical Chemistry at the Indian Institute of Science. He is known for his studies on mechanism of thyroid hormone action and is an elected fellow of the Indian Academy of Sciences, Indian National Science Academy, Royal Society of Chemistry and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to chemical sciences. In 2019, he was awarded the Infosys Prize in Physical Sciences for his seminal work in the chemical synthesis of small molecules and nanomaterials for biomedical applications.