Shubhasis Haldar was born in Suri (West Bengal) and had his early education in Durgapur. After finishing his Master of Science in Chemistry from Burdwan University, he moved to Indian Institute of Chemical Biology for his doctoral studies in the area of single molecule biophysics. After completion of his Ph.D., he joined Max Planck Institute of Biochemistry (Germany) as a postdoctoral fellow with Prof. Ulrich Hartl, where he directly measured the chain dynamics of proteins inside molecular chaperonin and confirmed the active cage model. Then he moved to Columbia University (United States) and started working with Prof. Julio Fernandez. In Columbia University, he showed the mechanical role of chaperones by which it assists the translation or translocation processes.